The overall goal of this research core is to understand the relationship between environmental exposures and human health by focusing research efforts on vulnerable human populations. In particular, the Pulmonary Biology and Disease Core facilitates the development and completion of collaborative studies in the areas of occupational and environmental lung disease. Consistent with the overall goals of this Core, the specific aims are to:

• Train promising young scientists who are interested in understanding how various aspects of human vulnerability (age, geographic factors, co-morbid diseases, nutritional status, economic status, race, or genetics) affect the relationship between environmental exposures and lung disease. A portion of the support for this training is obtained from established NIH supported training programs in environmental health, molecular/human genetics, and pulmonary pathobiology.
• Mentor young scientists and assist them in developing independent studies in environmental lung disease. Part of this support will be via Center-supported pilot grants; NIH training awards will also be pursued.
• Foster collaborative research among Center investigators.
• Function as consultants for scientists from any area to pursue studies related to the impact of vulnerability on the relationship between environmental exposures and environmental lung disease.
• Enhance communication among investigators interested in environmental lung disease.